Article
Disorganized olfactory bulb lamination in mice deficient for transcription factor AP-2epsilon.
Molecular and cellular neurosciences - 1 Nov 2009
Feng Weiguo, Simoes-de-Souza Fabio, Finger Thomas E, Restrepo Diego, Williams Trevor
Abstract excerpt
Within the olfactory bulb, neurons and their axonal connections are organized into distinct layers corresponding to different functionalities. Here we demonstrate that transcription factor AP-2epsilon is required for olfactory bulb development, specifically the establishment of appropriate neuronal lamination. During normal mouse embryogenesis, AP-2epsilon transcripts are one of the earliest markers of olfactory...
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