Article
Monogenic and Monoallelic Expression of Odorant Receptors.
Molecular pharmacology - 1 Nov 2016
Nagai Maíra H, Armelin-Correa Lucia Maria, Malnic Bettina
Abstract excerpt
Odorant receptors (ORs) belong to a large gene family of rhodopsin-like G protein-coupled receptors (GPCRs). The mouse OR gene family is composed of ∼1000 OR genes, and the human OR gene family is composed of ∼400 OR genes. The OR genes are spread throughout the genome, and can be found in clusters or as solitary genes in almost all chromosomes. These chemosensory GPCRs are expressed in highly specialized cells,...
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