Article
IL-6 promoter functional polymorphism -572C/G affects spontaneous clearance of hepatitis B virus infection.
Clinical laboratory - 1 Jan 2014
Lu Yanjun, Peng Jing, Wang Chunyu, Zhu Yaowu, Wang Feng, Sun Ziyong
Abstract excerpt
BACKGROUND: Recent research has shown the host innate immunity plays important roles in controlling HBV infec- tion, and interleukin-6 (IL-6) is the key factor involved in the innate immune response. It is well known that the polymorphisms of IL-6 promoter can affect both the transcription and production of IL-6. This study aims to investigate whether there is an association between the IL-6 promoter functional...
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