Article
IL-18 polymorphisms in hepatitis B virus related liver disease.
Cytokine - 1 Jun 2015
Karra Vijay Kumar, Gumma Phani Kumar, Chowdhury Soumya Jyoti, Ruttala Rajesh, Polipalli Sunil Kumar, Chakravarti Anita, Kar Premashis
Abstract excerpt
Interleukine-18 (IL-18) was originally called interferon (INF-γ) inducing factor and plays a critical dual role in Th1 polarization and viral clearance. We aimed to explore whether single-nucleotide promoter polymorphisms (SNPs) are associated with the outcome of hepatitis B virus (HBV) infection. 271 HBV infected patients were recruited in this study out of these 109 were spontaneously recovered and 162 were...
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