IL6 gene allele-specific C/EBPα-binding activity affects the development of HBV infection through modulation of Th17/Treg balance.

doi:10.1038/gene.2015.40

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

IL6 gene allele-specific C/EBPα-binding activity affects the development of HBV infection through modulation of Th17/Treg balance.

Genes and immunity - 1 Dec 2015

Zhang G, Wang W, Li S, Yang H, Zhang M, Zhang P, Wen Y, Wu A, Yang L, Zhou B, Chen X

Abstract excerpt

Interleukin-6 (IL-6) has an important role in the pathogenesis of chronic viral hepatitis and related liver diseases. Although host genetics associated with the response to anti-viral treatment have been reported, little is known about the relationship between IL6 genetic polymorphisms and the outcome of hepatitis B virus (HBV) infection. In this study, we determined the genotype distribution of rs1800796...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alanine Transaminase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CCAAT-Enhancer-Binding Proteins

Share to Hepatitis B

Share to HIV Infections

Share to Interleukin-6

Share to T-Lymphocytes, Regulatory

Share to Th17 Cells

Share to Viral Load

Source

Open in PubMed

Identifiers

PMID: 26447433
DOI: 10.1038/gene.2015.40

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IL6 gene allele-specific C/EBPα-binding activity affects the development of HBV infection through modulation of Th17/Treg balance.PMID 26447433Read ↗

Involvement of Interleukin 6 in Hepatitis B Viral Infection.Semantic proximity Read ↗

Genetic polymorphism of interleukin-6 influences susceptibility to HBV-related hepatocellular carcinoma in a male Chinese Han population.Semantic proximity Read ↗

Genetic Association of Interleukin-6 Polymorphism (rs1800796) with Chronic Hepatitis B Virus Infection in Chinese Han Population.Semantic proximity Read ↗

Rather than Rs1800796 polymorphism, expression of interleukin-6 is associated with disease progression of chronic HBV infection in a Chinese Han population.Semantic proximity Read ↗

IL-6(-572/-597) polymorphism and expression in HBV disease chronicity in an Indian population.Semantic proximity Read ↗

Genetic variants in IL4RA, IL6, and IL12B genes and susceptibility to hepatitis B and C virus infections among Iraqi patients.Semantic proximity Read ↗

Interleukin-6-174 Promoter Polymorphism and Susceptibility to Hepatitis B Virus Infection as a Risk Factor for Hepatocellular Carcinoma in Iran.Semantic proximity Read ↗

Genetic variants in IL-6 and IL-10 genes and susceptibility to hepatocellular carcinoma in HCV infected patients.Semantic proximity Read ↗

Genetic polymorphisms of interleukin-6 influence the development of hepatitis B virus-related liver cirrhosis in the Han Chinese populationSemantic proximity Read ↗

Association between interleukin 6 promoter variants and chronic hepatitis B progression.Semantic proximity Read ↗

Relationship between cytokine gene polymorphisms and chronic hepatitis B virus infection.Semantic proximity Read ↗

Relationship between interleukin-6 polymorphism and susceptibility to chronic hepatitis B virus infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.