Article
T-cell reactivity to wheat gluten in patients with insulin-dependent diabetes mellitus.
Scandinavian journal of immunology - 1 Jan 1998
Klemetti P, Savilahti E, Ilonen J, Akerblom H K, Vaarala O
Abstract excerpt
Dietary wheat gluten has been associated with the risk of diabetes in animal models of human insulin-dependent diabetes mellitus (IDDM). To evaluate the role of wheat gluten as a T cell antigen in human IDDM, we studied the cell-mediated immune response to wheat gluten in patients with IDDM and in control subjects. The cellular response to gluten was measured by the peripheral blood mononuclear cell (PBMC)...
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