Article
T-cell reactivity to insulin peptide A1-12 in children with recently diagnosed type 1 diabetes or multiple beta-cell autoantibodies.
Journal of autoimmunity - 1 Sept 2008
Marttila Jane, Huttunen Suvi, Vaarala Outi, Suzuki Kunimasa, Elliott John F, Närvänen Ale, Knip Mikael, Simell Olli, Ilonen Jorma
Abstract excerpt
Insulin-specific immune responses appear early in preclinical type 1 diabetes (T1D), and bovine insulin in cow's milk-based infant formulas has been suggested to be of importance in induction of the primary response to insulin in humans. To characterize insulin-specific T-cell reactivity we studi...
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