Article
Alpha-enolase is upregulated on the cell surface and responds to plasminogen activation in mice expressing a ∆133p53α mimic.
PloS one - 1 Jan 2015
Sawhney Sonal, Hood Kylie, Shaw Alisha, Braithwaite Antony W, Stubbs Richard, Hung Noelyn A, Royds Janice A, Slatter Tania L
Abstract excerpt
The p53 protein is a master regulator of the stress response. It acts as a tumor suppressor by inducing transcriptional activation of p53 target genes, with roles in apoptosis, cell cycle arrest and metabolism. The discovery of at least 12 isoforms of p53, some of which have tumor-promoting prope...
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