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Article

Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers.

PLoS genetics - 1 Feb 2015

Tonomura Noriko, Elvers Ingegerd, Thomas Rachael, Megquier Kate, Turner-Maier Jason, Howald Cedric, Sarver Aaron L, Swofford Ross, Frantz Aric M, Ito Daisuke, Mauceli Evan, Arendt Maja, Noh Hyun Ji, Koltookian Michele, Biagi Tara, Fryc Sarah, Williams Christina, Avery Anne C, Kim Jong-Hyuk, Barber Lisa, Burgess Kristine, Lander Eric S, Karlsson Elinor K, Azuma Chieko, Modiano Jaime F, Breen Matthew, Lindblad-Toh Kerstin

Abstract excerpt

Dogs, with their breed-determined limited genetic background, are great models of human disease including cancer. Canine B-cell lymphoma and hemangiosarcoma are both malignancies of the hematologic system that are clinically and histologically similar to human B-cell non-Hodgkin lymphoma and angi...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25642983
DOI: 10.1371/journal.pgen.1004922
PMCID: PMC4333733

Genes

STX8
TRPC6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25642983-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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