Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide association analysis of canine T zone lymphoma identifies link to hypothyroidism and a shared association with mast-cell tumors.

BMC genomics - 6 Jul 2020

Labadie Julia D, Elvers Ingegerd, Feigelson Heather Spencer, Magzamen Sheryl, Yoshimoto Janna, Dossey Jeremy, Burnett Robert, Avery Anne C

Abstract excerpt

BACKGROUND: T zone lymphoma (TZL), a histologic variant of peripheral T cell lymphoma, represents about 12% of all canine lymphomas. Golden Retrievers appear predisposed, representing over 40% of TZL cases. Prior research found that asymptomatic aged Golden Retrievers frequently have populations of T zone-like cells (phenotypically identical to TZL) of undetermined significance (TZUS), potentially representing a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Mammalian
Share to Dog Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Hypothyroidism

Share to Lymphoma, T-Cell, Peripheral

Share to Mast Cells

Share to Receptors, Thyrotropin

Source

Open in PubMed Open full text

Identifiers

PMID: 32631225
DOI: 10.1186/s12864-020-06872-9
PMCID: PMC7339439

Genes

SPAM1
DIO2
HYAL4
TSHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide association analysis of canine T zone lymphoma identifies link to hypothyroidism and a shared association with mast-cell tumors.PMID 32631225Read ↗

Genome-Wide Association Study of Golden Retrievers Identifies Germ-Line Risk Factors Predisposing to Mast Cell Tumours.Semantic proximity Read ↗

Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers.Semantic proximity Read ↗

Multi-omics approach identifies germline regulatory variants associated with hematopoietic malignancies in retriever dog breedsSemantic proximity Read ↗

Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background.Semantic proximity Read ↗

The tree that hides the forest: identification of common predisposing loci in several hematopoietic cancers and several dog breedsSemantic proximity Read ↗

Multi-omics approach identifies germline regulatory variants associated with hematopoietic malignancies in retriever dog breeds.Semantic proximity Read ↗

Identification of common predisposing loci to hematopoietic cancers in four dog breeds.Semantic proximity Read ↗

A Multi-Breed Genome-Wide Association Analysis for Canine Hypothyroidism Identifies a Shared Major Risk Locus on CFA12.Semantic proximity Read ↗

Molecular Profiling Reveals Prognostically Significant Subtypes of Canine LymphomaSemantic proximity Read ↗

Lymphoma in Border Collies: Genome-Wide Association and Pedigree AnalysisSemantic proximity Read ↗

Genome-Wide Analysis Identifies Germ-Line Risk Factors Associated with Canine Mammary Tumours.Semantic proximity Read ↗

Canine CD4+ T‐cell lymphoma identified by flow cytometry exhibits a consistent histomorphology and gene expression profileSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.