Article
Gene expression profiles of sporadic canine hemangiosarcoma are uniquely associated with breed.
PloS one - 20 May 2009
Tamburini Beth A, Trapp Susan, Phang Tzu Lip, Schappa Jill T, Hunter Lawrence E, Modiano Jaime F
Abstract excerpt
The role an individual's genetic background plays on phenotype and biological behavior of sporadic tumors remains incompletely understood. We showed previously that lymphomas from Golden Retrievers harbor defined, recurrent chromosomal aberrations that occur less frequently in lymphomas from other dog breeds, suggesting spontaneous canine tumors provide suitable models to define how heritable traits influence...
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