Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of common predisposing loci to hematopoietic cancers in four dog breeds.

PLoS genetics - 1 Apr 2021

Hédan Benoît, Cadieu Édouard, Rimbault Maud, Vaysse Amaury, Dufaure de Citres Caroline, Devauchelle Patrick, Botherel Nadine, Abadie Jérôme, Quignon Pascale, Derrien Thomas, André Catherine

Abstract excerpt

Histiocytic sarcoma (HS) is a rare but aggressive cancer in both humans and dogs. The spontaneous canine model, which has clinical, epidemiological, and histological similarities with human HS and specific breed predispositions, provides a unique opportunity to unravel the genetic basis of this cancer. In this study, we aimed to identify germline risk factors associated with the development of HS in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Cyclin-Dependent Kinase Inhibitor p16

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dog Diseases

Share to Genome-Wide Association Study

Share to Haplotypes

Share to Hematologic Neoplasms

Share to High-Throughput Nucleotide Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 33793571
DOI: 10.1371/journal.pgen.1009395
PMCID: PMC8016107

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of common predisposing loci to hematopoietic cancers in four dog breeds.PMID 33793571Read ↗

The tree that hides the forest: identification of common predisposing loci in several hematopoietic cancers and several dog breedsSemantic proximity Read ↗

The MTAP-CDKN2A locus confers susceptibility to a naturally occurring canine cancer.Semantic proximity Read ↗

Multi-omics approach identifies germline regulatory variants associated with hematopoietic malignancies in retriever dog breedsSemantic proximity Read ↗

Multi-omics approach identifies germline regulatory variants associated with hematopoietic malignancies in retriever dog breeds.Semantic proximity Read ↗

Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B.Semantic proximity Read ↗

Genome-Wide Analysis Identifies Germ-Line Risk Factors Associated with Canine Mammary Tumours.Semantic proximity Read ↗

Risk-modeling of dog osteosarcoma genome scans shows individuals with Mendelian-level polygenic risk are commonSemantic proximity Read ↗

Bringing the Genomic Revolution to Comparative Oncology: Human and Dog CancersSemantic proximity Read ↗

Analyses of canine cancer mutations and treatment outcomes using real-world clinico-genomics data of 2119 dogsSemantic proximity Read ↗

A monograph proposing the use of canine mammary tumours as a model for the study of hereditary breast cancer susceptibility genes in humansSemantic proximity Read ↗

Breed-Predispositions to Cancer in Pedigree DogsSemantic proximity Read ↗

Canine Cancer Genomics: Lessons for Canine and Human HealthSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.