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Article

Tyrosine kinase receptor B protects against coronary artery disease and promotes adult vasculature integrity by regulating Ets1-mediated VE-cadherin expression.

Arteriosclerosis, thrombosis, and vascular biology - 1 Mar 2015

Jiang Hong, Huang Shuhong, Li Xinyun, Li Xian, Zhang Yun, Chen Zhe-Yu

Abstract excerpt

OBJECTIVE: Tyrosine kinase receptor B (TrkB) is a high-affinity receptor for brain-derived neurotrophic factor. In addition to its nervous system functions, TrkB is also expressed in the cardiovascular system. However, the association of TrkB and coronary artery disease (CAD) remains unknown. We investigated the role of TrkB in the development of CAD and its mechanism. APPROACH AND RESULTS: We performed a...

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Source

Identifiers

PMID: 25633318
DOI: 10.1161/ATVBAHA.114.304405

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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