Article
TR3 orphan receptor is expressed in vascular endothelial cells and mediates cell cycle arrest.
Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 2003
Arkenbout E Karin, van Bragt Maaike, Eldering Eric, van Bree Chris, Grimbergen Jos M, Quax Paul H A, Pannekoek Hans, de Vries Carlie J M
Abstract excerpt
OBJECTIVE: Endothelial cells play a pivotal role in vascular homeostasis. In this study, we investigated the function of the nerve growth factor-induced protein-B (NGFI-B) subfamily of nuclear receptors comprising the TR3 orphan receptor (TR3), mitogen-induced nuclear orphan receptor (MINOR), and nuclear orphan receptor of T cells (NOT) in endothelial cells. METHODS AND RESULTS: The mRNA expression of TR3, MINOR,...
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