Article
Polymorphisms of KDR gene are associated with coronary heart disease.
Journal of the American College of Cardiology - 21 Aug 2007
Wang Yibo, Zheng Yi, Zhang Weili, Yu Hui, Lou Kejia, Zhang Yu, Qin Qin, Zhao Bingrang, Yang Ying, Hui Rutai
Abstract excerpt
OBJECTIVES: Our purpose was to determine whether the common polymorphisms (SNP-604, SNP1192, and SNP1719) in KDR are associated with risk of coronary heart disease. BACKGROUND: Vascular endothelial growth factor (VEGF) and its receptor KDR (kinase insert domain-containing receptor/fetal liver kinase-1, also called VEGFR2) play critical roles in angiogenesis and vascular repair, which are involved in the progress...
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