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Article

Structural requirements for the tissue-specific and tissue-general functions of the Caenorhabditis elegans epidermal growth factor LIN-3.

Genetics - 1 Nov 1999

Liu J, Tzou P, Hill R J, Sternberg P W

Abstract excerpt

Caenorhabditis elegans lin-3 encodes a homolog of the epidermal growth factor (EGF) family of growth factors. LIN-3 is the inductive signal for hermaphrodite vulval differentiation, and it is required for animal viability, hermaphrodite fertility, and the specification of anterior cell fates in the male B cell lineage. We describe the cloning of a lin-3 homolog from C. briggsae, sequence comparison of C. elegans...

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Identifiers

PMID: 10545457
DOI: 10.1093/genetics/153.3.1257
PMCID: PMC1460807

Genes

EGF

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Source receipt: pubmed, retrieved 7 Sept 2026.

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