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Article

The CD14 C-260T single nucleotide polymorphism (SNP) modulates monocyte/macrophage activation in treated HIV-infected individuals.

Journal of translational medicine - 27 Jan 2015

Rajasuriar Reena, Kong Yong Yean, Nadarajah Reshika, Abdullah Noor Kamila, Spelman Tim, Yuhana Muhamad Yazli, Ponampalavanar Sasheela, Kamarulzaman Adeeba, Lewin Sharon R

Abstract excerpt

BACKGROUND: HIV-infected individuals have an increased risk of cardiovascular disease (CVD). T-allele carriers of the CD14 C-260T single-nucleotide polymorphism (SNP) have reported increased expression of the LPS-binding receptor, CD14 and inflammation in the general population. Our aim was to explore the relationship of this SNP with monocyte/macrophage activation and inflammation and its association with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25622527
DOI: 10.1186/s12967-015-0391-6
PMCID: PMC4311493

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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