Article
Reduced CD14 expression on classical monocytes and vascular endothelial adhesion markers independently associate with carotid artery intima media thickness in chronically HIV-1 infected adults on virologically suppressive anti-retroviral therapy.
Atherosclerosis - 1 Jan 2014
Barbour Jason D, Jalbert Emilie C, Chow Dominic C, Gangcuangco Louie Mar A, Norris Philip J, Keating Sheila M, Heitman John, Nagamine Lorna, Seto Todd, Ndhlovu Lishomwa C, Nakamoto Beau K, Hodis Howard N, Parikh Nisha I, Shikuma Cecilia M
Abstract excerpt
HIV infection causes systemic immune inflammation, and increases the risk for cardiovascular (CVD) disease even among those on virologically suppressive anti-retroviral treatment (ART). We performed a biostatistical analysis and screen of candidate cellular and plasma biomarkers for association with carotid artery intima-media thickness (CIMT), independent of traditional CVD risk factors such as age, gender,...
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