Article
Role of toll-like receptor 4 Asp299Gly polymorphism in the development of cardiovascular diseases in HIV-infected patients.
AIDS (London, England) - 15 May 2018
Tarancon-Diez Laura, De Pablo-Bernal Rebeca S, Jiménez José L, Álvarez-Ríos Ana I, Genebat Miguel, Rosado-Sánchez Isaac, Muñoz-Fernández María-Ángeles, Ruiz-Mateos Ezequiel, Leal Manuel
Abstract excerpt
OBJECTIVE: Cardiovascular diseases (CVDs) are one of the main causes of morbimortality in HIV-infected patients on suppressive antiretroviral therapy. The objective of this work was to evaluate the role of single nucleotide polymorphisms (SNPs) in lipopolysaccharide (LPS) Toll-like receptor 4 (TLR4) and CVDs occurrence in HIV-infected patients. Additionally, the functional consequences of carrying these SNPs were...
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