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Article

High-resolution melting analysis of MED12 mutations in uterine leiomyomas in Chinese patients.

Genetic testing and molecular biomarkers - 1 Mar 2015

Wang Hua, Ye Jun, Qian Hua, Zhou Ruifang, Jiang Jun, Ye Lihua

Abstract excerpt

OBJECTIVES: Somatic mutations in mediator complex subunit 12 (MED12) have emerged as a critical genetic change in the development of uterine leiomyomas. Studies, however, have focused largely on cohorts consisting of Caucasian patients. In this study, uterine leiomyomas from Chinese patients were examined for MED12 mutations. In addition, polymerase chain reaction (PCR)-based high-resolution melting analysis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25615570
DOI: 10.1089/gtmb.2014.0273
PMCID: PMC4361005

Genes

MED12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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