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Rapid Identification of FGFR2 Gene Mutations in Taiwanese Patients With Endometrial Cancer Using High-resolution Melting Analysis.

Applied immunohistochemistry & molecular morphology : AIMM - 1 Aug 2015

Lin Yi-Ching, Er Tze-Kiong, Yeh Kun-Tu, Hung Chih-Hsing, Chang Jan-Gowth

Abstract excerpt

OBJECTIVES: Mutations in fibroblast growth factor receptor 2 (FGFR2) gene have been reported in endometrial cancer and mutant FGFR2 has been pointed out as a potential therapeutic target. The aim of the current study was to use a high-resolution melting (HRM) analysis to identify FGFR2 hotspot mutations and to investigate the occurrence of these mutations in the Taiwanese population with endometrial cancer....

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Identifiers

PMID: 25517871
DOI: 10.1097/PAI.0000000000000114

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FGFR2

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