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Article

Interaction association analysis of imputed SNPs in case-control and follow-up studies.

Genetic epidemiology - 1 Mar 2015

Subirana Isaac, González Juan R

Abstract excerpt

A new method is described to assess the interactions of imputed SNPs (single nucleotide polymorphisms) in case-control and follow-up studies, properly incorporating SNP imputation uncertainty in the likelihood model. Using simulation studies and analysis of real data obtained from the Framingham study cohort, we compare the performance of this new method to DOSAGE and NAIVE (also known as Best-Guess) methods,...

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PMID: 25613387
DOI: 10.1002/gepi.21883

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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