Article
The use of imputed values in the meta-analysis of genome-wide association studies.
Genetic epidemiology - 1 Nov 2011
Jiao Shuo, Hsu Li, Hutter Carolyn M, Peters Ulrike
Abstract excerpt
In genome-wide association studies (GWAS), it is a common practice to impute the genotypes of untyped single nucleotide polymorphism (SNP) by exploiting the linkage disequilibrium structure among SNPs. The use of imputed genotypes improves genome coverage and makes it possible to perform meta-analysis combining results from studies genotyped on different platforms. A popular way of using imputed data is the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
