Genetic association analysis and meta-analysis of imputed SNPs in longitudinal studies.

Abstract excerpt

In this paper we propose a new method to analyze time-to-event data in longitudinal genetic studies. This method address the fundamental problem of incorporating uncertainty when analyzing survival data and imputed single-nucleotide polymorphisms (SNPs) from genome-wide association studies (GWAS). Our method incorporates uncertainty in the likelihood function, the opposite of existing methods that incorporate the...

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