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Article

Comparison of multiple imputation and other methods for the analysis of imputed genotypes.

BMC genomics - 6 Jun 2023

Auer Paul L, Wang Gao, Li Guangyou, DeWan Andrew T, Leal Suzanne M

Abstract excerpt

BACKGROUND: Analysis of imputed genotypes is an important and routine component of genome-wide association studies and the increasing size of imputation reference panels has facilitated the ability to impute and test low-frequency variants for associations. In the context of genotype imputation, the true genotype is unknown and genotypes are inferred with uncertainty using statistical models. Here, we present a...

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PMID: 37277705
DOI: 10.1186/s12864-023-09415-0
PMCID: PMC10242917

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