Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bayesian epistasis association mapping via SNP imputation.

Biostatistics (Oxford, England) - 1 Apr 2011

Zhang Yu

Abstract excerpt

Genetic mutations may interact to increase the risk of human complex diseases. Mapping of multiple interacting disease loci in the human genome has recently shown promise in detecting genes with little main effects. The power of interaction association mapping, however, can be greatly influenced by the set of single nucleotide polymorphism (SNP) genotyped in a case-control study. Previous imputation methods only...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bayes Theorem
Share to Computer Simulation
Share to Epistasis, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to False Positive Reactions

Share to Inflammatory Bowel Diseases

Share to Markov Chains

Share to Monte Carlo Method

Source

Open in PubMed Open full text

Identifiers

PMID: 20923970
DOI: 10.1093/biostatistics/kxq063
PMCID: PMC3062153

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bayesian epistasis association mapping via SNP imputation.PMID 20923970Read ↗

Comparative analysis of methods for detecting interacting loci.Semantic proximity Read ↗

Imputation without doing imputation: a new method for the detection of non-genotyped causal variants.Semantic proximity Read ↗

A new multipoint method for genome-wide association studies by imputation of genotypes.Semantic proximity Read ↗

Novel Methods for Epistasis Detection in Genome-Wide Association StudiesSemantic proximity Read ↗

Modeling interactions with known risk loci-a Bayesian model averaging approach.Semantic proximity Read ↗

Detecting epistatic SNPs associated with complex diseases via a Bayesian classification tree search method.Semantic proximity Read ↗

Novel methods for epistasis detection in genome-wide association studies.Semantic proximity Read ↗

Imputation aware meta-analysis of genome-wide association studies.Semantic proximity Read ↗

Bayesian inference of epistatic interactions in case-control studies.Semantic proximity Read ↗

Screen and clean: a tool for identifying interactions in genome-wide association studies.Semantic proximity Read ↗

Searching Genome-Wide Multi-Locus Associations for Multiple Diseases Based on Bayesian Inference.Semantic proximity Read ↗

A fast algorithm for learning epistatic genomic relationships.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.