Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CD27low natural killer cells prolong allograft survival in mice by controlling alloreactive CD8+ T cells in a T-bet-dependent manner.

Transplantation - 1 Feb 2015

Lantow Margareta, Eggenhofer Elke, Sabet-Baktach Manije, Renner Philipp, Rovira Jordi, Koehl Gudrun E, Schlitt Hans J, Geissler Edward K, Kroemer Alexander

Abstract excerpt

BACKGROUND: Natural killer (NK) cells play a dichotomous role in alloimmune responses because they are known to promote both allograft survival and rejection. The aim of this study was to investigate the role of functionally distinct NK cell subsets in alloimmunity with the hypothesis that this dichotomy is explained by the functional heterogeneity of distinct NK cell subsets. METHODS: Because T-bet controls...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adoptive Transfer
Share to Graft Rejection

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Graft Survival

Share to Immunologic Memory

Share to Skin Transplantation

Share to T-bet Transcription Factor

Share to T-Box Domain Proteins

Share to Tumor Necrosis Factor Receptor Superfamily, Member 7

Source

Identifiers

PMID: 25606781
DOI: 10.1097/TP.0000000000000585

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CD27low natural killer cells prolong allograft survival in mice by controlling alloreactive CD8+ T cells in a T-bet-dependent manner.PMID 25606781Read ↗

CD27 Dissects Mature NK Cells into Two Subsets with Distinct Responsiveness and Migratory CapacitySemantic proximity Read ↗

γδ T cells are essential effectors of type 1 diabetes in the nonobese diabetic mouse model.Semantic proximity Read ↗

Therapeutic implications of NK cell regulation of allogeneic CD8 T cell-mediated immune responses stimulated through the direct pathway of antigen presentation in transplantation.Semantic proximity Read ↗

Functional Characteristics and Phenotypic Plasticity of CD57+PD1- CD4 T Cells and Their Relationship with Transplant Immunosuppression.Semantic proximity Read ↗

Dendritic cell-derived IL-27 p28 regulates T cell program in pathogenicity and alleviates acute graft-versus-host diseaseSemantic proximity Read ↗

p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytesSemantic proximity Read ↗

The transfer of adaptive immunity to CMV during hematopoietic stem cell transplantation is dependent on the specificity and phenotype of CMV-specific T cells in the donor.Semantic proximity Read ↗

A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy.Semantic proximity Read ↗

The B7-independent isoform of CTLA-4 functions to regulate autoimmune diabetes.Semantic proximity Read ↗

CD27-CD70 Costimulation Controls T Cell Immunity during Acute and Persistent Cytomegalovirus InfectionSemantic proximity Read ↗

Survival and function of CD47-deficient thymic grafts in mice.Semantic proximity Read ↗

Differential Impact of T-bet and IFNγ on Pancreatic Islet Allograft Rejection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.