Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Disruption of a conserved CAP-D3 threonine alters condensin loading on mitotic chromosomes leading to chromosome hypercondensation.

The Journal of biological chemistry - 6 Mar 2015

Bakhrebah Muhammed, Zhang Tao, Mann Jeff R, Kalitsis Paul, Hudson Damien F

Abstract excerpt

The condensin complex plays a key role in organizing mitotic chromosomes. In vertebrates, there are two condensin complexes that have independent and cooperative roles in folding mitotic chromosomes. In this study, we dissect the role of a putative Cdk1 site on the condensin II subunit CAP-D3 in chicken DT40 cells. This conserved site has been shown to activate condensin II during prophase in human cells, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphatases
Share to CDC2 Protein Kinase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chickens

Share to Chromatin

Share to Chromosomes

Share to Mitosis

Share to Multiprotein Complexes

Share to Threonine

Source

Open in PubMed Open full text

Identifiers

PMID: 25605712
DOI: 10.1074/jbc.M114.627109
PMCID: PMC4358255

Genes

INCENP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Disruption of a conserved CAP-D3 threonine alters condensin loading on mitotic chromosomes leading to chromosome hypercondensation.PMID 25605712Read ↗

Phosphorylation of CAP-G is required for its chromosomal DNA localization during mitosis.Semantic proximity Read ↗

The CDK Pef1 and Protein Phosphatase 4 oppose each other for regulating cohesin binding to fission yeast chromosomesSemantic proximity Read ↗

The Drosophila melanogaster condensin subunit Cap-G interacts with the centromere-specific histone H3 variant CID.Semantic proximity Read ↗

Phosphorylation of MCM4 by cdc2 protein kinase inhibits the activity of the minichromosome maintenance complex.Semantic proximity Read ↗

ATPase-dependent auto-phosphorylation of the open condensin hinge diminishes DNA binding.Semantic proximity Read ↗

An essential role for Cdk1 in S phase control is revealed via chemical genetics in vertebrate cells.Semantic proximity Read ↗

Mutations in the Drosophila condensin subunit dCAP-G: defining the role of condensin for chromosome condensation in mitosis and gene expression in interphase.Semantic proximity Read ↗

Rapid degradation and 3D CLEM of condensin reveal chromatin compaction uncoupled from chromosome architecture in mitosisSemantic proximity Read ↗

A role for condensin-mediator interaction in mitotic chromosome organization.Semantic proximity Read ↗

Mitotic phosphorylation of histone H3 threonine 80.Semantic proximity Read ↗

Cyclin A2/Cdk1 is Essential for the <i>in vivo</i> S Phase Entry by Phosphorylating Top2aSemantic proximity Read ↗

Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.