Article
The Drosophila melanogaster condensin subunit Cap-G interacts with the centromere-specific histone H3 variant CID.
Chromosoma - 1 Feb 2005
Jäger Hubert, Rauch Melanie, Heidmann Stefan
Abstract excerpt
The centromere-specific histone H3 variant CENP-A plays a crucial role in kinetochore specification and assembly. We chose a genetic approach to identify interactors of the Drosophila CENP-A homolog CID. Overexpression of cid in the proliferating eye imaginal disk results in a rough eye phenotype, which is dependent on the ability of the overexpressed protein to localize to the kinetochore. A screen for modifiers...
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