Article
Indolamine 2,3-dioxygenase expression by monocytes and dendritic cell populations in hepatitis C patients.
Clinical and experimental immunology - 1 Jun 2015
Schulz S, Landi A, Garg R, Wilson J A, van Drunen Littel-van den Hurk S
Abstract excerpt
Dendritic cells (DCs) play an important role in the induction of the primary immune response to infection. DCs may express the tryptophan-catabolizing enzyme indolamine2,3-dioxygenase (IDO), which is an inducer of immune tolerance. Because there is evidence that chronic hepatitis C virus (HCV) infection leads to functional impairment of certain DC populations, we analysed IDO expression in DCs and monocytes from...
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