Article
Spb1p is a yeast nucleolar protein associated with Nop1p and Nop58p that is able to bind S-adenosyl-L-methionine in vitro.
Molecular and cellular biology - 1 Feb 2000
Pintard L, Kressler D, Lapeyre B
Abstract excerpt
We present here the characterization of SPB1, an essential yeast gene that is required for ribosome synthesis. A cold-sensitive allele for that gene (referred to here as spb1-1) had been previously isolated as a suppressor of a mutation affecting the poly(A)-binding protein gene (PAB1) and a thermosensitive allele (referred to here as spb1-2) was isolated in a search for essential genes required for gene...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Conserved Sequence
- DNA Primers
- Evolution, Molecular
- Fungal Proteins
- Gene Deletion
- Genes, Fungal
- Genetic Complementation Test
- Methyltransferases
- Molecular Sequence Data
- Mutation
- Nuclear Proteins