Article
Correct assembly of RNA polymerase II depends on the foot domain and is required for multiple steps of transcription in Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Sept 2013
Garrido-Godino A I, García-López M C, Navarro F
Abstract excerpt
Recent papers have provided insight into the cytoplasmic assembly of RNA polymerase II (RNA pol II) and its transport to the nucleus. However, little is known about the mechanisms governing its nuclear assembly, stability, degradation, and recycling. We demonstrate that the foot of RNA pol II is crucial for the assembly and stability of the complex, by ensuring the correct association of Rpb1 with Rpb6 and of the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
