Memory efficient assembly of human genome.

Abstract excerpt

The ability to detect the genetic variations between two individuals is an essential component for genetic studies. In these studies, obtaining the genome sequence of both individuals is the first step toward variation detection problem. The emergence of high-throughput sequencing (HTS) technology has made DNA sequencing practical, and is widely used by diagnosticians to increase their knowledge about the casual...

Topics

• Algorithms
• Animals
• Computational Biology
• Computer Simulation
• Genome, Human
• High-Throughput Nucleotide Sequencing
• Humans
• Mice
• Mice, Inbred A
• Mutation
• Polymorphism, Single Nucleotide