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Article

Efficiently detecting polymorphisms during the fragment assembly process.

Bioinformatics (Oxford, England) - 1 Jan 2002

Fasulo Daniel, Halpern Aaron, Dew Ian, Mobarry Clark

Abstract excerpt

MOTIVATION: Current genomic sequence assemblers assume that the input data is derived from a single, homogeneous source. However, recent whole-genome shotgun sequencing projects have violated this assumption, resulting in input fragments covering the same region of the genome whose sequences differ due to polymorphic variation in the population. While single-nucleotide polymorphisms (SNPs) do not pose a...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 12169559
DOI: 10.1093/bioinformatics/18.suppl_1.s294

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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