Regional brain [(11)C]carfentanil binding following tobacco smoking.

doi:10.1016/j.pnpbp.2015.01.007

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Article

Regional brain [(11)C]carfentanil binding following tobacco smoking.

Progress in neuro-psychopharmacology & biological psychiatry - 3 Jun 2015

Domino Edward F, Hirasawa-Fujita Mika, Ni Lisong, Guthrie Sally K, Zubieta Jon Kar

Abstract excerpt

OBJECTIVE: To determine if overnight tobacco abstinent carriers of the AG or GG (*G) vs. the AA variant of the human mu opioid receptor (OPRM1) A118G polymorphism (rs1799971) differ in [(11)C]carfentanil binding after tobacco smoking. METHODS: Twenty healthy American male smokers who abstained from tobacco overnight were genotyped and completed positron emission tomography (PET) scans with the mu opioid receptor...

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Identifiers

PMID: 25598501
DOI: 10.1016/j.pnpbp.2015.01.007
PMCID: PMC4375952

Genes

OPRM1

Variants

rs1799971

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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