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Article

Effects of nicotine deprivation and replacement on BOLD-fMRI response to smoking cues as a function of DRD4 VNTR genotype.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco - 1 Jul 2014

Xu Xiaomeng, Clark Uraina S, David Sean P, Mulligan Richard C, Knopik Valerie S, McGeary John, MacKillop James, McCaffery Jeanne, Niaura Raymond S, Sweet Lawrence H

Abstract excerpt

INTRODUCTION: Reactivity to smoking cues is an important factor in the motivation to smoke and has been associated with the dopamine receptor 4 variable number tandem repeat (DRD4 exon III VNTR) polymorphism. However, little is known about the associated neural mechanisms. METHODS: Non-treatment-seeking Caucasian smokers completed overnight abstinence and viewed smoking and neutral cues during 2 separate...

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Source

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Identifiers

PMID: 24659022
DOI: 10.1093/ntr/ntu010
PMCID: PMC4072897

Genes

DRD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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