Antibacterial Efficacy of R-Type Pyocins towards <i>Pseudomonas aeruginosa</i> in a Murine Peritonitis Model

Abstract excerpt

R-type pyocins are high-molecular-weight bacteriocins carried within the chromosomes of some bacterial species, such as Pseudomonas aeruginosa, and almost certainly evolved from lysogenic bacteriophages of the Myoviridae family. They contain no head structures and no DNA and are used as defense systems, usually against other strains of the same bacterial species. They bind with their tail fibers to targeted...