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Article

Strategies for quorum sensing inhibition as a tool for controlling Pseudomonas aeruginosa infections

4 Sept 2024

Abstract excerpt

• Promising alternative antimicrobial therapeutic strategies focus on blocking bacterial processes unrelated to viability. • Inhibiting bacterial communication by targeting the quorum sensing (QS) system blocks virulence pathways activation and biofilm formation. • Strategies to disrupt the P. aeruginosa QS system include disrupting QS signalling molecule (autoinducers, AIs) biosynthetic pathways. • Few QS...

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PMID: 39242051
DOI: 10.1016/j.ijantimicag.2024.107323

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