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Article

Motor activity in young APPswe + PS1/A246E bigenic mice as a predicting variable for memory decline.

Journal of neuroscience research - 1 Jun 2015

Filali Mohammed, Lalonde Robert

Abstract excerpt

Reports of individuality in rodent species have been a subject of debate in pharmacology and other fields. In the current study, APPswe + PS1/A246E bigenic mice with Alzheimer's-like pathogenesis and wild-type controls were subdivided at 3 months of age into low, intermediate, and high responders in open-field activity. The mice were then evaluated longitudinally at 3 and 9 months for object recognition....

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Identifiers

PMID: 25594937
DOI: 10.1002/jnr.23552

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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