Article
Chronic neutrophilic leukemia: novel mutations and their impact on clinical practice.
Current opinion in hematology - 1 Mar 2015
Tefferi Ayalew, Elliott Michelle, Pardanani Animesh
Abstract excerpt
PURPOSE OF REVIEW: Chronic neutrophilic leukemia (CNL) is a rare BCR-ABL1-negative myeloid malignancy that is characterized by mature granulocytosis without dysgranulopoiesis. Differential diagnosis of CNL includes reactive or secondary granulocytosis and other myeloid neoplasms, such as atypical chronic myeloid leukemia (aCML) and chronic myelomonocytic leukemia (CMML). Herein, we focus on recently described...
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