Article
The molecular genetics of chronic neutrophilic leukaemia: defining a new era in diagnosis and therapy.
Current opinion in hematology - 1 Mar 2014
Elliott Michelle A, Tefferi Ayalew
Abstract excerpt
PURPOSE OF REVIEW: In the current WHO classification of myeloid disorders, chronic neutrophilic leukaemia (CNL) is recognized as a myeloproliferative neoplasm characterized by sustained neutrophilic leukocytosis, hepatosplenomegaly and bone marrow granulocytic hyperplasia without evidence of dysplasia, BCR-ABL1 or rearrangements of PDGFRA, PDGFRB or FGFR1. This diagnosis is contingent upon exclusion of underlying...
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