Article
Chronic neutrophilic leukemia: 2018 update on diagnosis, molecular genetics and management.
American journal of hematology - 1 Aug 2018
Elliott Michelle A, Tefferi Ayalew
Abstract excerpt
DISEASE OVERVIEW AND DIAGNOSIS: Chronic neutrophilic leukemia (CNL) is a potentially aggressive myeloproliferative neoplasm, for which current WHO diagnostic criteria include leukocytosis of ≥ 25 x 109 /L of which ≥ 80% are neutrophils, with < 10% circulating neutrophil precursors with blasts rarely observed. In addition, there is no dysplasia, nor clinical or molecular criteria for other myeloproliferative...
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