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Article

Genomics of chronic neutrophilic leukemia.

Blood - 9 Feb 2017

Maxson Julia E, Tyner Jeffrey W

Abstract excerpt

Chronic neutrophilic leukemia (CNL) is a distinct myeloproliferative neoplasm with a high prevalence (>80%) of mutations in the colony-stimulating factor 3 receptor (CSF3R). These mutations activate the receptor, leading to the proliferation of neutrophils that are a hallmark of CNL. Recently, the World Health Organization guidelines have been updated to include CSF3R mutations as part of the diagnostic criteria...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Colony-Stimulating Factor

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Source

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Identifiers

PMID: 28028025
DOI: 10.1182/blood-2016-10-695981
PMCID: PMC5301820

Genes

SETBP1
ASXL1
SRSF2
TET2

Provenance

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