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Chronic neutrophilic leukemia 2014: Update on diagnosis, molecular genetics, and management

20 May 2014

Abstract excerpt

DISEASE OVERVIEW: Chronic neutrophilic leukemia (CNL) is a myeloproliferative neoplasm characterized by sustained, mature neutrophilic leukocytosis, splenomegaly, and bone marrow granulocytic hyperplasia. DIAGNOSIS: Key diagnostic criteria include leukocytosis of >25 × 10(9) /l (of which >80% are neutrophils) with <10% and <1% circulating immature granulocytes and myeloblasts, respectively. There should be no...

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PMID: 24845374
DOI: 10.1002/ajh.23667

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