Article
Characterization of a cytochalasin D-resistant mutant of Entamoeba histolytica.
The Journal of protozoology - 1 Jan 2000
de la Garza M, Gallegos B, Meza I
Abstract excerpt
Characterization of a cytochalasin D-resistant mutant of the human parasite Entamoeba histolytica capable of growing at 10 microM cytochalasin is described. The mutant cells also show resistance to 5 mM colchicine and 100 microM cytochalasin B, drugs proved deleterious for wild type trophozoites. The mutants show increased osmotic fragility and electric mobility but reduced phagocytic activity, and agglutination...
Topics
- Actins
- Animals
- Cytochalasin D
- Drug Resistance
- Entamoeba histolytica
- Mutation
- Osmotic Fragility
- Phagocytosis
- Pinocytosis
- Surface Properties