Entamoeba histolytica: correlation of the cytopathic effect of virulent trophozoites with secretion of a cysteine proteinase.

doi:10.1016/0014-4894(90)90022-5

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Article

Entamoeba histolytica: correlation of the cytopathic effect of virulent trophozoites with secretion of a cysteine proteinase.

Experimental parasitology - 1 Aug 1990

Keene W E, Hidalgo M E, Orozco E, McKerrow J H

Abstract excerpt

Work from several laboratories suggests a correlation between expression of cysteine proteinase activity and the cytopathic effect of virulent HM1 strain Entamoeba histolytica trophozoites on cultured cell monolayers. Consistent with this relationship, we find that L-6 trophozoites, mutants clone...

Topics

Animals
Cell Line
Cysteine Endopeptidases
Cysteine Proteinase Inhibitors
Entamoeba histolytica
Mutation
Virulence

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