Article
A unique Rab GTPase, EhRabA, is involved in motility and polarization of Entamoeba histolytica cells.
Molecular and biochemical parasitology - 1 Apr 2005
Welter Brenda H, Powell Rhonda R, Leo Megan, Smith Christine M, Temesvari Lesly A
Abstract excerpt
Entamoeba histolytica, an enteric protozoan parasite, infects 10% of the world's population leading to 50 million cases of invasive amoebiasis annually. Motility, which requires cell polarization, is important to the virulence of this pathogen, as it may result in destruction of host tissues and invasion. To gain insight into these processes in Entamoeba, a unique Rab GTPase, EhRabA, which localizes to the...
Topics
- Actins
- Animals
- CHO Cells
- Cell Adhesion
- Cricetinae
- Entamoeba histolytica
- Intracellular Space
- Lectins
- Movement
- Mutation
- Protozoan Proteins
- Virulence Factors
- rab GTP-Binding Proteins