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Article

Ionophore-resistant mutants of Toxoplasma gondii reveal host cell permeabilization as an early event in egress.

Molecular and cellular biology - 1 Dec 2000

Black M W, Arrizabalaga G, Boothroyd J C

Abstract excerpt

Toxoplasma gondii is an obligate intracellular pathogen within the phylum Apicomplexa. Invasion and egress by this protozoan parasite are rapid events that are dependent upon parasite motility and appear to be directed by fluctuations in intracellular [Ca(2+)]. Treatment of infected host cells with the calcium ionophore A23187 causes the parasites to undergo rapid egress in a process termed ionophore-induced...

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Identifiers

PMID: 11094090
DOI: 10.1128/MCB.20.24.9399-9408.2000
PMCID: PMC102196

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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