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Article

A genetic screen to isolate Toxoplasma gondii host-cell egress mutants.

Journal of visualized experiments : JoVE - 8 Feb 2012

Coleman Bradley I, Gubbels Marc-Jan

Abstract excerpt

The widespread, obligate intracellular, protozoan parasite Toxoplasma gondii causes opportunistic disease in immuno-compromised patients and causes birth defects upon congenital infection. The lytic replication cycle is characterized by three stages: 1. active invasion of a nucleated host cell; 2. replication inside the host cell; 3. active egress from the host cell. The mechanism of egress is increasingly being...

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Identifiers

PMID: 22349295
DOI: 10.3791/3807
PMCID: PMC3350636

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Source receipt: pubmed, retrieved 7 Sept 2026.

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A genetic screen to isolate Toxoplasma gondii host-cell egress mutants.PMID 22349295Read ↗

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