Article
Host genetic variations in glutathione-S-transferases, superoxide dismutases and catalase genes influence susceptibility to malaria infection in an Indian population.
Molecular genetics and genomics : MGG - 1 Jun 2015
Fernandes Rayzel C, Hasan Marriyah, Gupta Himanshu, Geetha K, Rai Padmalatha S, Hande Manjunath H, D'Souza Sydney C, Adhikari Prabha, Brand Angela, Satyamoorthy Kapaettu
Abstract excerpt
Antioxidant enzymes can contribute to disease susceptibility or determine response to therapy in individuals with malaria. Genetic variations due to polymorphisms in host genes encoding antioxidant enzymes such as glutathione S-transferases-theta, mu, pi (GSTT, GSTM, GSTP), superoxide dismutases (SOD) and catalase (CAT), may therefore, influence inter-individual response to malaria pathology and propensity of...
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